Multiple methods within a single trial [Regulatives / Guidelines]

posted by Ohlbe – France, 2019-03-13 18:21 (948 d 16:01 ago) – Posting: # 20025
Views: 3,824

Dear Osama,

» on the other hand, The use of two methods or technologies within a
» comparative BA/BE study is strongly discouraged:. (i.e not applicable at all also with cross-validation).:confused::confused:
» Why ??

I would reverse the question: why would you use two different methods, or two different technologies, within a single BE trial, with the risk of increasing variability ? We're not talking of 2 different trials here (where one can be done at one CRO and the other at another CRO, with a different method).

Regards
Ohlbe

Complete thread:

Activity
 Admin contact
21,730 posts in 4,544 threads, 1,543 registered users;
online 5 (0 registered, 5 guests [including 4 identified bots]).
Forum time: Sunday 11:22 CEST (Europe/Vienna)

Be very, very careful what you put into that head,
because you will never, ever get it out.    Thomas Wolsey

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5