Multiple methods within a single trial [Regulatives / Guidelines]

posted by Ohlbe – France, 2019-03-13 19:21 (2165 d 15:28 ago) – Posting: # 20025
Views: 5,750

Dear Osama,

❝ on the other hand, The use of two methods or technologies within a

comparative BA/BE study is strongly discouraged:. (i.e not applicable at all also with cross-validation).:confused::confused:

❝ Why ??


I would reverse the question: why would you use two different methods, or two different technologies, within a single BE trial, with the risk of increasing variability ? We're not talking of 2 different trials here (where one can be done at one CRO and the other at another CRO, with a different method).

Regards
Ohlbe

Complete thread:

UA Flag
Activity
 Admin contact
23,380 posts in 4,914 threads, 1,665 registered users;
83 visitors (0 registered, 83 guests [including 8 identified bots]).
Forum time: 10:49 CET (Europe/Vienna)

When people learn no tools of judgment
and merely follow their hopes,
the seeds of political manipulation are sown.    Stephen Jay Gould

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5