Bioequivalence and Bioavailability Forum

Hi ElMaestro,

First of all I don't know the answer.
But I'm recalling some similar situation when emmeans package couldn't compute lsmeans but gives good solution for the difference. Moreover, the concept of subject nested within sequence didn't work for lsmeans

I mailed to the author (Russel Lenth) and we discussed the problem. Some weeks later he updated the package and the problem was resolved. But you should be ready to share some example.
Hope it helps.

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Edit: Package linked. [Helmut]