PowerTOST: CVfromCI [Study As­sess­ment]

posted by Rosy – Mexico, 2019-02-20 15:25  – Posting: # 19939
Views: 3,648

(edited by Rosy on 2019-02-20 15:37)

»              Not interested in other members’ opinions?

I'm sorry if I looked rude, I was just trying to follow the thread of the publication ... of course, I'm interested in any opinion. My deepest apologies to everyone.

» Parallel‽

I had a miscomprehension of the statistical analysis, i read again and they used an ANOVA included the following factors: sequence (SEQ), subject nested within sequence (SUBJECT [SEQ]), period (PHASE), and treatment (TREAT). I though that they maked a paired comparation, one at time.

But in this case: https://accp1.onlinelibrary.wiley.com/doi/abs/10.1177/009127009903901108?sid=nlm%3Apubmed

The study had an open-label, single-dose, three-way crossover design. Subjects were randomly assigned to receive one of three treatments per period

Design: 3x2 N= 17

A vs B ----> IC (84.9-106)
A vs C ----> IC (169-211)
B vs C ----> IC (178-222)

How to calculate %CV Intra-individual???

100*CVfromCI(lower=0.849, upper=1.06, n=17, design='2x2x3', alpha=0.05)

it's that correct???

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