CV values in BE studies: intra, or inter, or total? [Study As­sess­ment]

posted by Rosy – Mexico, 2019-02-19 18:33 (949 d 09:30 ago) – Posting: # 19934
Views: 8,409

Dear Helmut,

Accordig to the first post, i have a doubt. If i found an article of a BABE study in which 3 formulation where evaluated against to reference (A) in a 4 way crossover study, but in a bioequivalence table appears for example A vs B treatment and its respective Geometric Mean Ratio (IC 90%). If i wanna calculate CV% intrasubject ussing POWER.TOST which desing i have to pick up (4x4 or parallel)? Of course 4x4 is the real design but the comparative A vs B is technically a parallel study.

Kind Regards

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