CV values in BE studies: intra, or inter, or total? [Study As­sess­ment]

posted by Rosy – Mexico, 2019-02-19 19:33 (1885 d 12:28 ago) – Posting: # 19934
Views: 10,529

Dear Helmut,

Accordig to the first post, i have a doubt. If i found an article of a BABE study in which 3 formulation where evaluated against to reference (A) in a 4 way crossover study, but in a bioequivalence table appears for example A vs B treatment and its respective Geometric Mean Ratio (IC 90%). If i wanna calculate CV% intrasubject ussing POWER.TOST which desing i have to pick up (4x4 or parallel)? Of course 4x4 is the real design but the comparative A vs B is technically a parallel study.

Kind Regards

Complete thread:

UA Flag
Activity
 Admin contact
22,987 posts in 4,824 threads, 1,663 registered users;
82 visitors (0 registered, 82 guests [including 6 identified bots]).
Forum time: 09:01 CEST (Europe/Vienna)

The only way to comprehend what mathematicians mean by Infinity
is to contemplate the extent of human stupidity.    Voltaire

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5