Dose curve [PK / PD]

posted by Sundar.M – India, 2019-02-15 12:37 (707 d 06:50 ago) – Posting: # 19925
Views: 1,015

Dear all,

How to choose dose for any PK/PD study (without non-clinical data) in healthy volunteer for Phase-1 trials for already marketed product? Other words, how to choose the proposed dose to detect clinically meaningful differences in PK/PD responses?

Thanks for your help.


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