Bioequivalence and Bioavailability Forum

ANOVA fixed and random effects [General Sta­tis­tics]

posted by Babe_Ruth – USA, 2019-02-08 20:46  – Posting: # 19893
Views: 1,140

Hi ElMaestro

» Yikes. Do you mean single ascending doses, mutiple ascending doses? That would likely make this a first in man, potentially?? I am not sure I would like to offer opinions on those. Is the API very well known??

Yes, that's what I meant with SAD and MAD. Yes, first in human. API is not known, but the its target is pretty hot these days. They call her Jaki.

» "Subject in sequence" ... only has relevance if you don't number subjects uniquely.

whoa, mind blown. Applied to my question above, "Subject as a random effect" is the same as "Subject nested in treatment condition (Fed/Fasted)"? Given that subject numbers are all unique.

» I tend to bang my head into the table when it happens.

This explains both your intelligence and your insanity =D

Complete thread:

• ANOVA fixed and random effects Babe_Ruth 2019-02-08 18:32 [General Sta­tis­tics] 
  • ANOVA fixed and random effects ElMaestro 2019-02-08 19:00
    • ANOVA fixed and random effects Babe_Ruth 2019-02-08 19:53
      • ANOVA fixed and random effects ElMaestro 2019-02-08 20:24
        • ANOVA fixed and random effects Babe_Ruth 2019-02-08 20:46
          • Food effect in FIM Ohlbe 2019-02-08 22:58