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posted by Helmut 
– Vienna, Austria, 2019-02-04 16:34 (2697 d 22:09 ago) – Posting: # 19862
Views: 12,083
Hi Nastia,
Veto!
Look up ‘trough’ in an English dictionary. A kind of minimum, right? The minimum (hence in the textbooks “Cmin”) can occur anywhere in the profile. If you have no lag-time the chance to observe it at the beginning and the end is 50% each (by definition).
I’m fine with the term Cτ,ss cause it is unambigous. IMHO, the term Ctrough shouldn’t be used at all.
Définissez les termes, vous dis-je, ou jamais nous ne nous entendrons.
❝ […] By def Ctrough occurs at the end of dosing interval... I give up... It is impossible to distinguish!
Veto!
Look up ‘trough’ in an English dictionary. A kind of minimum, right? The minimum (hence in the textbooks “Cmin”) can occur anywhere in the profile. If you have no lag-time the chance to observe it at the beginning and the end is 50% each (by definition).
I’m fine with the term Cτ,ss cause it is unambigous. IMHO, the term Ctrough shouldn’t be used at all.
Définissez les termes, vous dis-je, ou jamais nous ne nous entendrons.
Define your terms, you will permit me again to say, or we shall never understand one another.
Voltaire (Miracles, 1764)
—
Dif-tor heh smusma 🖖🏼 Довге життя Україна!![[image]](https://static.bebac.at/pics/Blue_and_yellow_ribbon_UA.png)
Helmut Schütz
![[image]](https://static.bebac.at/img/CC by.png)
The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes
Dif-tor heh smusma 🖖🏼 Довге життя Україна!
Helmut Schütz
The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes
Complete thread:
- Steady state: Cmin / PTF Helmut 2011-03-08 15:30 [NCA / SHAM]
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Steady state: Cmin / PTF SDavis 2012-02-06 14:00
- Steady state: Cmin / PTF Helmut 2012-02-06 14:24
- Is Cmin an atavism or not? Astea 2019-02-03 22:25
- Originators | generics (Cmin | Cτ) Helmut 2019-02-04 13:18
- Down with Big Brother Astea 2019-02-04 13:51
- Down with Big Brother Helmut 2019-02-04 14:43
- thoughtcrime Astea 2019-02-04 15:13
- blackwhiteHelmut 2019-02-04 15:34
- animal farm Astea 2019-02-04 15:53
- blackwhiteHelmut 2019-02-04 15:34
- thoughtcrime Astea 2019-02-04 15:13
- Down with Big Brother Helmut 2019-02-04 14:43
- Down with Big Brother Astea 2019-02-04 13:51
- Originators | generics (Cmin | Cτ) Helmut 2019-02-04 13:18
- Is Cmin an atavism or not? Astea 2019-02-03 22:25
- Steady state: Cmin / PTF Helmut 2012-02-06 14:24
- Steady state: Cmin / PTF SDavis 2012-02-06 14:00
Ing. Helmut Schütz