LSMeans, still causing lots of people headaches [General Sta­tis­tics]

posted by ElMaestro  – Denmark, 2019-02-03 19:39 (2277 d 22:17 ago) – Posting: # 19851
Views: 4,907

Hellobi :-D,

and thanks for helping towards an understanding.

I am a bit confused, what is ln[T] in your terminology?
Is it individual measurements, or effects form the b-vector or is it the average on the ln scale?
And what is the starting point for this?

Also, residuals -once a linear model has been fit to the least squares criterion- sum to zero, right? I got confused when you went from step 4 to 5.


❝ The Model Residual is the variance for the difference of LSMeans between Ln[T] and Ln[R].


Why?
I would think it is the plain uncertainty for an (within-) effect estimate in the b vector when we talk crossovers. Multiply by two and you have the variance of the difference or something like that.

Pass or fail!
ElMaestro

Complete thread:

UA Flag
Activity
 Admin contact
23,424 posts in 4,927 threads, 1,667 registered users;
14 visitors (0 registered, 14 guests [including 10 identified bots]).
Forum time: 18:56 CEST (Europe/Vienna)

Garbage in, garbage out.
It’s very very simple.    Anders Fuglsang

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5