Bioequivalence and Bioavailability Forum • R-Code for Power in 2×2 Cross-over

R-Code for Power in 2×2 Cross-over [🇷 for BE/BA]

posted by Ohlbe – France, 2019-01-27 19:24 (2333 d 15:23 ago) – Posting: # 19814
Views: 22,119

Dear KDA,

❝ Q1) If it is 2x2 cross-over study, test and ref drug would be given only once. Can we get true intra-subject co-efficient of variance (CV)from 2x2 cross-over study?

No. You need a replicate design study.

I'll let others answer Q5.

—
Regards
Ohlbe

Complete thread:

R-Code for Power in 2×2 Cross-over Helmut 2006-12-28 21:33 [🇷 for BE/BA]
- Power in Diletti's sample size table Helmut 2007-01-01 23:59
  - Approximate Power Helmut 2007-01-06 15:17
    - Power Calculation for replicate crossover design mathews 2008-04-03 13:19
      - Power Calculation for replicate crossover design Helmut 2008-04-03 13:49
        
        Power Calculation for replicate crossover design mathews 2008-04-04 13:21
    - Exact Power Helmut 2009-09-25 19:20
      - Exact Power ElMaestro 2009-09-27 23:27
        
        Software validation Helmut 2009-09-28 15:21
        
        All the important answers are here! ElMaestro 2009-09-28 19:12
        
        All the important answers are here! Helmut 2009-09-28 19:52
        
        All the important answers are here! ElMaestro 2009-09-28 20:18
        All the important answers are here! yjlee168 2009-09-28 21:30
        
        All the important answers are here! Helmut 2009-09-28 23:18
        
        42! SASophylistic power oracle d_labes 2009-09-29 13:37
        
        Al Gore Rhythms Helmut 2009-09-29 14:52
        
        Al Gore Rhythms ElMaestro 2009-09-29 18:14
        Al Gore Rhythms yjlee168 2009-09-29 23:55
        
        All the important answers are here! yjlee168 2009-09-29 23:49
- R-Code for Power in 2×2 Cross-over KDA 2019-01-23 04:24
  - R-Code for Power in 2×2 Cross-overOhlbe 2019-01-27 18:24
- R-Code for Power in 2×2 Cross-over Brus 2021-12-02 15:00
  - R-Code for Power in 2×2 Cross-over ElMaestro 2021-12-02 15:15
    - R-Code for Power in 2×2 Cross-over Helmut 2021-12-02 17:30
  - R-Code for Power in 2×2 Cross-over Helmut 2021-12-02 16:57