Interference from Deuterated IS [Bioanalytics]
Hello chirag,
may I ask:
Does the IS increase or decrease the area of the analyte?
What is the purity expressed as DigD3 on your CoA's?
may I ask:
❝ 2.During method development we observed around 12-16% interference from Digoxin deuterated (D3) IS at the RT of Digoxin drug. There seems to be no source for D5 or D7 or D11.
Does the IS increase or decrease the area of the analyte?
❝ 4. Two different sources of Deuterated IS were tested and results are similar.
What is the purity expressed as DigD3 on your CoA's?
—
Pass or fail!
ElMaestro
Pass or fail!
ElMaestro
Complete thread:
- Interference from Deuterated IS cakhatri 2019-01-10 07:20 [Bioanalytics]
- Interference from Deuterated IS VKB2207 2019-01-10 20:48
- Interference from Deuterated IS Ohlbe 2019-01-10 22:36
- Interference from Deuterated IS Ohlbe 2019-01-10 23:41
- Interference from Deuterated IS cakhatri 2019-01-11 09:28
- Interference from Deuterated ISElMaestro 2019-01-11 09:49
- Interference from Deuterated IS VKB2207 2019-01-10 20:48