Interference from Deuterated IS [Bioanalytics]

posted by VKB2207 – Portugal, 2019-01-10 20:48 (1051 d 03:55 ago) – Posting: # 19767
Views: 2,831


Suggest you not to go with MV in this scenario as IS is contributing and you have no exact idea how much it is contributing. Hence measured concentrations would be inaccurate.

You can probably evaluate the % contribution from IS at RT of drug and then apply this factor in CC, QC nominal concentrations.

Hope it helps.


Edit: Full quote removed. Please delete everything from the text of the original poster which is not necessary in understanding your answer; see also this post! [Ohlbe]

Complete thread:

 Admin contact
21,778 posts in 4,555 threads, 1,547 registered users;
online 13 (0 registered, 13 guests [including 9 identified bots]).
Forum time: Saturday 00:44 CET (Europe/Vienna)

Every new technology to me is like a newborn baby –
and you think that it’s become president
or it’s cure cancer or win a nobel prize.
But in the end, you’re perfectly happy
when it just stays out of jail […].    Eric Betzig

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz