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SearchInterference from Deuterated IS [Bioanalytics]
Hi,
Suggest you not to go with MV in this scenario as IS is contributing and you have no exact idea how much it is contributing. Hence measured concentrations would be inaccurate.
You can probably evaluate the % contribution from IS at RT of drug and then apply this factor in CC, QC nominal concentrations.
Hope it helps.
Regards
Edit: Full quote removed. Please delete everything from the text of the original poster which is not necessary in understanding your answer; see also this post! [Ohlbe]
Suggest you not to go with MV in this scenario as IS is contributing and you have no exact idea how much it is contributing. Hence measured concentrations would be inaccurate.
You can probably evaluate the % contribution from IS at RT of drug and then apply this factor in CC, QC nominal concentrations.
Hope it helps.
Regards
Edit: Full quote removed. Please delete everything from the text of the original poster which is not necessary in understanding your answer; see also this post! [Ohlbe]
Complete thread:
- Interference from Deuterated IS - cakhatri, 2019-01-10 07:20 [Bioanalytics]
![[Mix]](https://static.bebac.at/img/mix.png "open in mix view")
- Interference from Deuterated IS - VKB2207, 2019-01-10 20:48
- Interference from Deuterated IS - Ohlbe, 2019-01-10 22:36
- Interference from Deuterated IS - Ohlbe, 2019-01-10 23:41
- Interference from Deuterated IS - cakhatri, 2019-01-11 09:28
- Interference from Deuterated IS - ElMaestro, 2019-01-11 09:49
- Interference from Deuterated IS - VKB2207, 2019-01-10 20:48
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