Power.TOST and "3x3" [🇷 for BE/BA]

posted by ElMaestro  – Denmark, 2019-01-08 17:29 (1932 d 23:26 ago) – Posting: # 19760
Views: 4,290

Dear all,
or perhaps mainly the powerTOST authors and maintainers :-D

thanks a lot for power.TOST and related functions. They are great.

I have a question about e.g.

> power.TOST(CV=.3, theta0=.95, n=30, design="3x3")
[1] 0.6973262


Is that the chance of showing BE for one of the comparisons, for two comparisons if we assume two are tests formulations and one if ref, or is it "all against all" which is also a common comparison?

Now, I am asking because theta0 seems to be a single number, not a vector.
Imagine we have formulations A, B and C; if true ratios for A/B and B/C are 0.95 then in my little simple universe the true ratio for A/C is ~0.9. Therefore, I imagine it is not for all against all (3 comparisons in my case).

So I wonder what goes on behind the curtains in R when I give the command above and how I should interpret the output here. I read the documentation and did not see an obvious answer but I am also not so well versed with power.TOST.

Many thanks for any input.
Or output, depending on your perspective.:-D

Pass or fail!
ElMaestro

Complete thread:

UA Flag
Activity
 Admin contact
22,993 posts in 4,828 threads, 1,659 registered users;
64 visitors (0 registered, 64 guests [including 4 identified bots]).
Forum time: 17:56 CEST (Europe/Vienna)

So far as I can remember,
there is not one word in the Gospels
in praise of intelligence.    Bertrand Russell

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5