Distribution to erythrocytes of Methylphenidate [Bioanalytics]

posted by EKY – Thailand, 2019-01-04 03:08  – Posting: # 19727
Views: 434

According to available data that methylphenidate and its metabolites are distributed between plasma (57%) and erythrocytes (43%) in blood.

In the bioanalysis for quantification of methylphenidate in plasma, there are some hemolysis samples.

Has anyone experienced that hemolysis samples (plasma) affect the bioanalysis or the reported plasma concentrations?

Can the respective plasma concentrations from hemolysis samples be fallacious?

Best Regards,

Complete thread:

Activity
 Mix view
Bioequivalence and Bioavailability Forum |  Admin contact
19,265 posts in 4,098 threads, 1,314 registered users;
online 16 (0 registered, 16 guests [including 5 identified bots]).

Competence, like truth, beauty and contact lenses,
is in the eye of the beholder.    Laurence J. Peter

The BIOEQUIVALENCE / BIOAVAILABILITY FORUM is hosted by
BEBAC Ing. Helmut Schütz
HTML5