Distribution to erythrocytes of Methylphenidate [Bioanalytics]

posted by EKY – Thailand, 2019-01-04 03:08  – Posting: # 19727
Views: 947

According to available data that methylphenidate and its metabolites are distributed between plasma (57%) and erythrocytes (43%) in blood.

In the bioanalysis for quantification of methylphenidate in plasma, there are some hemolysis samples.

Has anyone experienced that hemolysis samples (plasma) affect the bioanalysis or the reported plasma concentrations?

Can the respective plasma concentrations from hemolysis samples be fallacious?

Best Regards,

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