Distribution to erythrocytes of Methylphenidate [Bioanalytics]

posted by EKY – Thailand, 2019-01-04 03:08 (1109 d 14:07 ago) – Posting: # 19727
Views: 1,929

According to available data that methylphenidate and its metabolites are distributed between plasma (57%) and erythrocytes (43%) in blood.

In the bioanalysis for quantification of methylphenidate in plasma, there are some hemolysis samples.

Has anyone experienced that hemolysis samples (plasma) affect the bioanalysis or the reported plasma concentrations?

Can the respective plasma concentrations from hemolysis samples be fallacious?

Best Regards,

Complete thread:

Activity
 Admin contact
21,829 posts in 4,566 threads, 1,555 registered users;
online 6 (0 registered, 6 guests [including 6 identified bots]).
Forum time: Monday 17:16 CET (Europe/Vienna)

Discovery consists of seeing what everybody has seen
and thinking what nobody has thought.    Albert Szent-Györgyi

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5