AUC or Cmax for RSABE? [Power / Sample Size]

posted by BE-proff – 2018-12-24 18:58 (1943 d 12:01 ago) – Posting: # 19714
Views: 2,889

Hi All,:ok:

let's say I want to conduct a BE study using RSABE (EMA).
From previous studies I have both AUCs and Cmax with their GMR and CVintra.

Which parameter is better for sample size calculation - AUC or Cmax?

Complete thread:

UA Flag
Activity
 Admin contact
22,988 posts in 4,825 threads, 1,654 registered users;
86 visitors (0 registered, 86 guests [including 4 identified bots]).
Forum time: 08:00 CEST (Europe/Vienna)

The whole purpose of education is
to turn mirrors into windows.    Sydney J. Harris

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5