Bioequivalence and Bioavailability Forum

AUC or Cmax for RSABE? [Power / Sample Size]

posted by BE-proff – Russia, 2018-12-24 17:58  – Posting: # 19714
Views: 636

Hi All,

let's say I want to conduct a BE study using RSABE (EMA).
From previous studies I have both AUCs and Cmax with their GMR and CVintra.

Which parameter is better for sample size calculation - AUC or Cmax?

Complete thread:

• AUC or Cmax for RSABE? BE-proff 2018-12-24 17:58 
  • Take them both mittyri 2018-12-24 21:33