PK metrics: Calculation using SAS Software [Software]

posted by d_labes  – Berlin, Germany, 2018-12-23 19:33 (2386 d 05:56 ago) – Posting: # 19710
Views: 4,850

Dear Sury,

❝ As i have only SAS Software with me right now by i want to calculate the PK parameters which can be only done through WinNonlin software


I think that statement isn't true. Since SAS is a multipurpose statistical language you may also be able to calculate the PK metrics within that.

❝ ...can anyone have the code for calculating the Paremeters like AUCt, AUCinf, Kel and Thalf using SAS code. if anyone have the code please share it.


See this old paper (2005):
https://www.lexjansen.com/pharmasug/2005/StatisticsPharmacokinetics/sp07.pdf

And see also this old thread (2006).

But take all this sayings and code with a grain of salt. See it as a starting point for your own code.
Many special situations like missing values or values below LLOQ are not covered.
Additionally the ability to react on errors. Nearly not possible with SAS.

Regards,

Detlew

Complete thread:

UA Flag
Activity
 Admin contact
23,427 posts in 4,929 threads, 1,677 registered users;
21 visitors (0 registered, 21 guests [including 10 identified bots]).
Forum time: 02:30 CEST (Europe/Vienna)

Many people tend to look at programming styles and languages like religions:
if you belong to one, you cannot belong to others.
But this analogy is another fallacy.    Niklaus Wirth

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5