PE vs GMR [R for BE/BA]

posted by Ohlbe – France, 2018-12-11 00:28  – Posting: # 19676
Views: 3,234

Dear roman_max,

» My question is: does PE and GMR represent different metrics, numerically and/or statistically?

Yes.

» On the one hand GMR by definition is a ratio of LSM T/LSM R

No. This is PE. The GMR is the ratio of geometric means, not of LSM (LSMEAN in SAS-speak). For more details on how to calculate LSM and the difference between LSM and geometric mean, see this oldie.

PE and GMR will be identical if you have a balanced study (same number of subjects in sequence RT and sequence TR). If the study is unbalanced (e.g. if you have a dropout), you'll get different results. The difference is usually minimal, but can be more important if you have an outlier.

Regards
Ohlbe

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