recoveries more than 100% [Bioanalytics]
Hello Ladi and Deepak,
The % recovery across all concentration levels (i.e LOW ,MED add High) should be consistent that means %CV should be within 20% across all levels and also you should mentioned the accepted % recovery range (i.e from 30% to 120%) in your SOP and this high % recovery might be due to ion enhancement , sample preparation error etc. and also it is acceptable as per FDA guideline.(limit for % recovery is not mentioned in FDA Guideline)
Thank You,
Kintan Patel
Edit: Full quote removed. Please delete everything from the text of the original poster which is not necessary in understanding your answer; see also this post! [Ohlbe]
The % recovery across all concentration levels (i.e LOW ,MED add High) should be consistent that means %CV should be within 20% across all levels and also you should mentioned the accepted % recovery range (i.e from 30% to 120%) in your SOP and this high % recovery might be due to ion enhancement , sample preparation error etc. and also it is acceptable as per FDA guideline.(limit for % recovery is not mentioned in FDA Guideline)
Thank You,
Kintan Patel
Edit: Full quote removed. Please delete everything from the text of the original poster which is not necessary in understanding your answer; see also this post! [Ohlbe]
Complete thread:
- recoveries more than 100% deepakpangavhane 2018-09-03 08:28 [Bioanalytics]
- recoveries more than 100% Ohlbe 2018-09-03 19:21
- recoveries more than 100% Ladi 2018-09-04 03:51
- recoveries more than 100%Kintan Patel 2018-11-29 11:48
- Origin of figures ? Ohlbe 2018-11-30 18:23
- Origin of figures ? Kintan Patel 2018-12-05 10:04
- Origin of figures ? Ohlbe 2018-12-05 10:30
- Origin of figures ? Kintan Patel 2018-12-05 10:04
- Origin of figures ? Ohlbe 2018-11-30 18:23
- recoveries more than 100%Kintan Patel 2018-11-29 11:48