recoveries more than 100% [Bioanalytics]

posted by Kintan Patel – India, 2018-11-29 11:48  – Posting: # 19659
Views: 1,001

Hello Ladi and Deepak,

The % recovery across all concentration levels (i.e LOW ,MED add High) should be consistent that means %CV should be within 20% across all levels and also you should mentioned the accepted % recovery range (i.e from 30% to 120%) in your SOP and this high % recovery might be due to ion enhancement , sample preparation error etc. and also it is acceptable as per FDA guideline.(limit for % recovery is not mentioned in FDA Guideline)

Thank You,
Kintan Patel

Edit: Full quote removed. Please delete everything from the text of the original poster which is not necessary in understanding your answer; see also this post! [Ohlbe]

Complete thread:

 Mix view
Bioequivalence and Bioavailability Forum |  Admin contact
19,478 posts in 4,133 threads, 1,333 registered users;
online 11 (0 registered, 11 guests [including 5 identified bots]).
Forum time (Europe/Vienna): 21:20 CEST

But it is in matters beyond the limits of mere rule
that the skill of the analyst is evinced.
He makes in silence a host of observations and inferences…    Edgar Allan Poe

BEBAC Ing. Helmut Schütz