recoveries more than 100% [Bioanalytics]

posted by Kintan Patel – India, 2018-11-29 11:48  – Posting: # 19659
Views: 1,227

Hello Ladi and Deepak,

The % recovery across all concentration levels (i.e LOW ,MED add High) should be consistent that means %CV should be within 20% across all levels and also you should mentioned the accepted % recovery range (i.e from 30% to 120%) in your SOP and this high % recovery might be due to ion enhancement , sample preparation error etc. and also it is acceptable as per FDA guideline.(limit for % recovery is not mentioned in FDA Guideline)

Thank You,
Kintan Patel


Edit: Full quote removed. Please delete everything from the text of the original poster which is not necessary in understanding your answer; see also this post! [Ohlbe]

Complete thread:

Activity
 Mix view
Bioequivalence and Bioavailability Forum |  Admin contact
19,619 posts in 4,161 threads, 1,341 registered users;
online 6 (1 registered, 5 guests [including 5 identified bots]).
Forum time (Europe/Vienna): 05:23 CEST

Statistics: The science of producing unreliable facts
from reliable figures.    Evan Esar

The BIOEQUIVALENCE / BIOAVAILABILITY FORUM is hosted by
BEBAC Ing. Helmut Schütz
HTML5