Bioequivalence and Bioavailability Forum 01:10 CET

Main page Policy/Terms of Use Abbreviations Latest Posts

 Log in |  Register |  Search

Larger difference between upper and lower limit of 90% CI [Power / Sample Size]

posted by mirza baig - Mumbai, India, 2018-11-28 16:14  - Posting: # 19654
Views: 520

Hello Everyone,

I am new comer on this forum working in bio equivalence department so I just wanted to know that If we got larger difference between 90% CI limit for any primary factor like AUC0-t, AUC 0-infinity or Cmax e.g. lower limit is 90% and upper limit is 120% so what could be the predictions about the factors that widen the limit (both factor in vitro or in vivo).


Response will be highly appreciated


Edit: category changed [Ohlbe]

Complete thread:

Activity
 Mix view
Bioequivalence and Bioavailability Forum |  Admin contact
19,154 posts in 4,080 threads, 1,308 registered users;
online 15 (0 registered, 15 guests [including 11 identified bots]).

One can show the following: given any rule, however “fundamental”
or “necessary” for science, there are always circumstances
when it is advisable not only to ignore the rule,
but to adopt its opposite.    Paul Feyerabend

The BIOEQUIVALENCE / BIOAVAILABILITY FORUM is hosted by
BEBAC Ing. Helmut Schütz
HTML5 RSS Feed