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RegisterLarger difference between upper and lower limit of 90% CI [Power / Sample Size]
Hello Everyone,
I am new comer on this forum working in bio equivalence department so I just wanted to know that If we got larger difference between 90% CI limit for any primary factor like AUC0-t, AUC 0-infinity or Cmax e.g. lower limit is 90% and upper limit is 120% so what could be the predictions about the factors that widen the limit (both factor in vitro or in vivo).
Response will be highly appreciated
Edit: category changed [Ohlbe]
I am new comer on this forum working in bio equivalence department so I just wanted to know that If we got larger difference between 90% CI limit for any primary factor like AUC0-t, AUC 0-infinity or Cmax e.g. lower limit is 90% and upper limit is 120% so what could be the predictions about the factors that widen the limit (both factor in vitro or in vivo).
Response will be highly appreciated
Edit: category changed [Ohlbe]
Complete thread:
- Larger difference between upper and lower limit of 90% CImirza baig 2018-11-28 16:14 [Power / Sample Size]
![[Mix]](https://static.bebac.at/img/mix.png "open in Mix view")
- Larger difference between upper and lower limit of 90% CI Ohlbe 2018-11-28 23:49
Ing. Helmut Schütz