Larger difference between upper and lower limit of 90% CI [Power / Sample Size]

posted by mirza baig  – Mumbai, India, 2018-11-28 17:14 (1947 d 08:24 ago) – Posting: # 19654
Views: 2,958

Hello Everyone,

I am new comer on this forum working in bio equivalence department so I just wanted to know that If we got larger difference between 90% CI limit for any primary factor like AUC0-t, AUC 0-infinity or Cmax e.g. lower limit is 90% and upper limit is 120% so what could be the predictions about the factors that widen the limit (both factor in vitro or in vivo).


Response will be highly appreciated


Edit: category changed [Ohlbe]

Complete thread:

UA Flag
Activity
 Admin contact
22,957 posts in 4,819 threads, 1,636 registered users;
75 visitors (0 registered, 75 guests [including 8 identified bots]).
Forum time: 01:39 CET (Europe/Vienna)

With four parameters I can fit an elephant,
and with five I can make him wiggle his trunk.    John von Neumann

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5