Bioequivalence and Bioavailability Forum

EMA: Mahalanobis distance is dead... [Dissolution / BCS / IVIVC]

posted by ElMaestro  – Denmark, 2018-11-09 20:12 (2164 d 08:45 ago) – Posting: # 19559
Views: 7,844

Thanks Hötzi,

I applaud that move.
Bootstrapping has enormous potential, not just for dissolution. Sometimes the idea behind bootstrapping to me appears so simple and naïve that I am thinking it must be wrong . Especially considering how often we complicate simple issues with fancy maths.

So due to this step in the right direction I'll put flags on the table tonight and celebrate.

Complete thread:

• EMA: Mahalanobis distance is dead... Helmut 2018-11-09 18:01 [Dissolution / BCS / IVIVC] 
  • EMA: Mahalanobis distance is dead...ElMaestro 2018-11-09 19:12
    • Is ƒ2 dead as well – always bootstrapping? Helmut 2019-10-06 15:27
      • Is ƒ2 dead as well – always bootstrapping? ElMaestro 2019-10-06 17:54
        • Ahem – number of units? Helmut 2019-10-06 18:14
          • Ahem – number of units? ElMaestro 2019-10-06 22:45
            • Ahem – number of units? wienui 2019-10-07 19:11
            • Ahem – number of units? elba.romero 2021-10-28 00:08
          • Ahem – number of units - ICH M9 Relaxation 2021-10-28 16:20