Bioequivalence and Bioavailability Forum • EMA: Mahalanobis distance is dead...

EMA: Mahalanobis distance is dead... [Dissolution / BCS / IVIVC]

posted by Helmut – Vienna, Austria, 2018-11-09 19:01 (2411 d 13:03 ago) – Posting: # 19558
Views: 11,316

... and bootstrapping is alive.

See Question and answer on the adequacy of the Mahalanobis distance to assess the comparability of drug dissolution profiles.

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Complete thread:

EMA: Mahalanobis distance is dead...Helmut 2018-11-09 18:01 [Dissolution / BCS / IVIVC]
- EMA: Mahalanobis distance is dead... ElMaestro 2018-11-09 19:12
  - Is ƒ2 dead as well – always bootstrapping? Helmut 2019-10-06 15:27
    - Is ƒ2 dead as well – always bootstrapping? ElMaestro 2019-10-06 17:54
      - Ahem – number of units? Helmut 2019-10-06 18:14
        
        Ahem – number of units? ElMaestro 2019-10-06 22:45
        
        Ahem – number of units? wienui 2019-10-07 19:11
        Ahem – number of units? elba.romero 2021-10-28 00:08
        
        Ahem – number of units - ICH M9 Relaxation 2021-10-28 16:20

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