Purpose of S:N? [Bioanalytics]

posted by Helmut Homepage – Vienna, Austria, 2018-11-08 09:46 (1325 d 03:08 ago) – Posting: # 19545
Views: 6,243

Hi ElMaestro,

» » [...] two methods, A/P at the LLOQ 20/20%, S/N 10 or 15/15 5?
»
» I don't follow this terminology, can you explain what you mean? My hindsight is 20/20.

Sorry, my wording was not clear. I meant: Both methods fullfil the required conditions for (in)accuracy and precision at the LLOQ (20%). The first one is right at the border (20/20) but with a nice S:N of 10. The second one is better in terms of A/C (15/15) despite a worse S:N of 5.
I guess most people would prefer #2. I don't see the purpose of S:N. IMHO, it is nice to know only.

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