Yes it went a little fast [Bioanalytics]

posted by nobody – 2018-11-07 19:30 (1601 d 01:36 ago) – Posting: # 19544
Views: 6,567

Formally, the limit of detection (LOD) is defined by the S:N ratio. The peak you can definitely distinguish from noise (Limit of blank) with your method. In bioanalytics the LLOQ is by definition the concentration you can determine with P/A of 20%/+/-20% (by a convention method, i.e spiked samples with n=......).

If you (or anybody else in the room...) think your LOD is higher than the LLOQ, you have a problem, in deed. Otherwise... see Helllcourages statement.

Kindest regards, nobody

Complete thread:

UA Flag
Activity
 Admin contact
22,553 posts in 4,724 threads, 1,606 registered users;
13 visitors (0 registered, 13 guests [including 5 identified bots]).
Forum time: 22:07 CEST (Europe/Vienna)

Learning of many things
does not teach intelligence.    Heraclitus of Ephesus

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5