Bioequivalence and Bioavailability Forum • Yes it went a little fast

Yes it went a little fast [Bioanalytics]

posted by ElMaestro – Belgium?, 2018-11-06 11:10 (753 d 18:34 ago) – Posting: # 19541
Views: 4,980

Hello nobody,

» But in my opinion the solution has to fit the problem you are addressing. Otherwise there would already be a DIN/ISO in place, or? :-D

»
» s:n is frequently a problem in trace analytics...

Clever remark.
Feel free to make assumptions, change data, and feel free to assume it is a spiked plasma sample at the LLOQ in a bioaalytical validation or feel free to make any other assumption that allows you to think you have a solution to the question.

I am curious as to what the solution is, as in, how exctly is signal and noise quantified (once I have that I think I can make the division myself, but I am not even 100% sure about it).

—
I could be wrong, but...

Best regards,
ElMaestro

No, of course you do not need to audit your CRO if it was inspected in 1968 by the agency of Crabongostan.

Complete thread:

Isn't it time for an open source chromatographic format ElMaestro 2018-11-04 21:54 [Bioanalytics]
- Isn't it time for an open source chromatographic format nobody 2018-11-05 09:00
  - and now that we are at it ElMaestro 2018-11-05 13:53
    - and now that we are at it nobody 2018-11-05 16:33
      - and now that we are at it ElMaestro 2018-11-05 18:19
    - Transparent ruler – like in the good ol’ days Helmut 2018-11-05 20:39
      - Transparent ruler – like in the good ol’ days Ohlbe 2018-11-05 22:14
        
        Transparent ruler – like in the good ol’ days ElMaestro 2018-11-05 22:43
        
        Slow down, you move too fast […] Feelin’ Groovy Helmut 2018-11-06 02:05
        
        Slow down, you move too fast […] Feelin’ Groovy nobody 2018-11-06 09:29
        
        Yes it went a little fast ElMaestro 2018-11-06 11:09
        
        Yes it went a little fast nobody 2018-11-06 12:05
        
        Yes it went a little fastElMaestro 2018-11-06 12:10
        
        Yes it went a little fast Helmut 2018-11-07 16:09
        
        Yes it went a little fast ElMaestro 2018-11-07 16:22
        
        Yes it went a little fast nobody 2018-11-07 18:30
        Purpose of S:N? Helmut 2018-11-08 09:46
        
        Purpose of S:N? ElMaestro 2018-11-08 22:27
        
        Purpose of S:N? nobody 2018-11-09 10:06
        
        Purpose of S:N? Helmut 2018-11-09 11:34
        
        Purpose of S:N? nobody 2018-11-09 12:08
        
        Purpose of S:N? Helmut 2018-11-09 12:34
        
        Purpose of S:N? Helmut 2018-11-09 11:26
        
        Purpose of S:N? ElMaestro 2018-11-09 13:16
- Isn't it time for an open source chromatographic format paulhurleyuk 2018-11-05 16:27