Yes it went a little fast [Bioanalytics]

posted by ElMaestro  – Belgium?, 2018-11-06 11:09 (757 d 20:25 ago) – Posting: # 19539
Views: 4,892

Hello nobody,

» May I ask what we are doing here? Is this example peak the lowest calibration point? Or do you want to determine s:n for a patient sample (why?)?

This was just a digression.
I asked noone in particular what s:n is and gave a example of a fictive simulated chromatogram on which the forum's experts could practice their skills and demonstrate knowledge.
Shouldn't have done it. But now that you are here, what is in your idea of s:n ? How do you calculate it?

Whether the series respresents an LLOQ or a PK sample or something entirely different is immaterial to this discussion.

So.... what is s:n in your opinion? How would you prefer to quantify the level of noise and the level of signal?

I could be wrong, but...

Best regards,

No, of course you do not need to audit your CRO if it was inspected in 1968 by the agency of Crabongostan.

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