Gutting PowerTOST [🇷 for BE/BA]

posted by GM – India, 2018-11-03 06:09 (1963 d 01:16 ago) – Posting: # 19525
Views: 3,405

Hi Helmut,

❝ not Detlew but answering anyway. ;-)


Thank you for quick reply at every time.:-)

❝ So why are you not simply using it?

library(PowerTOST)

❝ sampleN.RSABE(CV=0.4, theta0=0.9, targetpower=0.8, design="2x2x4")

If you want further information about the arguments and their defaults, type ?sampleN.RSABE in the R-console / R-Studio’s console or consult the online manual.


As this is a replicated study, there are only few articles for calculating the sample size.
There is no clear information about this. So that, I suppose to understand concept through R-program.

I have few more doubts, regarding the terms CVswitch, r_const and pe_constr.

I thought CVswitch=0.30 for both FDA and EMA, r_const=0.25 and 0.760 for FDA and EMA respectively and don't know about the pe_constr.

Kindly correct me if I am wrong...

Thank you in advance.

Best Regards,
GM

Complete thread:

UA Flag
Activity
 Admin contact
22,940 posts in 4,812 threads, 1,640 registered users;
48 visitors (1 registered, 47 guests [including 7 identified bots]).
Forum time: 07:25 CET (Europe/Vienna)

Those people who think they know everything
are a great annoyance to those of us who do.    Isaac Asimov

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5