About the Partial SS in Boequivalence results in WinNonlin 8.1 [Software]
Dear All,
I have some questions about the Partial SS in Bioequivalence results in WinNonlin.
Firstly, why the Partial SS results just provided under default model(2x2x2 design) in WinNonlin 8.1? It just provides the Partial test worksheet in other models. What are the differences and relationship between the Partial test results and Partial SS results?
Secondly, what are the Numer_DF and Denom_DF? What is the calculation method for these DF since it could be decimals in Degrees of freedom sometimes. Just like the following results:
Dependent Units Hypothesis Numer_DF Denom_DF F_stat P_value
Ln(AUClast) int 1 17.863275 2.012866 0.17318289
Ln(AUClast) Sequence 1 17.876226 9.2107972 0.007163829
Ln(AUClast) Formulation 1 17.189233 0.19446307 0.66472393
Ln(AUClast) Period 1 17.202333 0.67862197 0.42133666
Could you kindky help me with these questions?
Thank you very much,
Fu Yangyang
Edit: Category changed; see also this post #1. [Mittyri]
I have some questions about the Partial SS in Bioequivalence results in WinNonlin.
Firstly, why the Partial SS results just provided under default model(2x2x2 design) in WinNonlin 8.1? It just provides the Partial test worksheet in other models. What are the differences and relationship between the Partial test results and Partial SS results?
Secondly, what are the Numer_DF and Denom_DF? What is the calculation method for these DF since it could be decimals in Degrees of freedom sometimes. Just like the following results:
Dependent Units Hypothesis Numer_DF Denom_DF F_stat P_value
Ln(AUClast) int 1 17.863275 2.012866 0.17318289
Ln(AUClast) Sequence 1 17.876226 9.2107972 0.007163829
Ln(AUClast) Formulation 1 17.189233 0.19446307 0.66472393
Ln(AUClast) Period 1 17.202333 0.67862197 0.42133666
Could you kindky help me with these questions?
Thank you very much,
Fu Yangyang
Edit: Category changed; see also this post #1. [Mittyri]
Complete thread:
- About the Partial SS in Boequivalence results in WinNonlin 8.1fyy897854960 2018-11-01 09:28
- About the Partial SS in Boequivalence results in WinNonlin 8.1 mittyri 2018-11-01 11:50
- About the Partial SS in Boequivalence results in WinNonlin 8.1 fyy897854960 2018-11-01 14:16
- About the Partial SS in Boequivalence results in WinNonlin 8.1 ElMaestro 2018-11-01 22:49
- RTFM Helmut 2018-11-01 23:12
- Hidden features of WNL Bioequivalence mittyri 2018-11-02 11:19
- About the Partial SS in Boequivalence results in WinNonlin 8.1 mittyri 2018-11-01 11:50