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Spiramycine [Bioanalytics]

posted by giang nidqc - Vietnam, 2018-09-27 08:55  - Posting: # 19329
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Dear all,
I've been looking for any guidance of BE study for spiramycine but have not found anything. I found some articles, some used microbiological assay, some used HPLC methods (detect all 3 components or only Spiramycine I). As spiramycine have 3 main components (I: 85%, II: 5%; III: 10%), all have therapeutic effect, what APIs do we need to measure: all of these components individually, or just Spiramycine I?
THanks in advance!

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