Spiramycine [Bioanalytics]

posted by giang nidqc – Vietnam, 2018-09-27 08:55  – Posting: # 19329
Views: 439

Dear all,
I've been looking for any guidance of BE study for spiramycine but have not found anything. I found some articles, some used microbiological assay, some used HPLC methods (detect all 3 components or only Spiramycine I). As spiramycine have 3 main components (I: 85%, II: 5%; III: 10%), all have therapeutic effect, what APIs do we need to measure: all of these components individually, or just Spiramycine I?
THanks in advance!

Complete thread:

Activity
 Mix view
Bioequivalence and Bioavailability Forum |  Admin contact
19,265 posts in 4,098 threads, 1,314 registered users;
online 11 (1 registered, 10 guests [including 6 identified bots]).

Competence, like truth, beauty and contact lenses,
is in the eye of the beholder.    Laurence J. Peter

The BIOEQUIVALENCE / BIOAVAILABILITY FORUM is hosted by
BEBAC Ing. Helmut Schütz
HTML5