Group Effect in Full Replicate Design [RSABE / ABEL]

posted by Helmut Homepage – Vienna, Austria, 2018-09-12 17:31 (1540 d 02:28 ago) – Posting: # 19278
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Hi GM,

❝ ❝ For the ABE part (if swR <0.294) like the FDA’s Model II:



❝ But as per Progesterone Guidance, Treatment as random term in Average BE.


No way.

❝ Please see model SAS code from guidance.


MODEL LAUCT = SEQ PER TRT/ DDFM=SATTERTH;

❝ RANDOM TRT/TYPE=FA0(2) SUB=SUBJ G;


Please make yourself familiar with the syntax of SAS’ PROC MIXED. Terms in the MODEL argument are fixed.

❝ As per your version, Subject (nested within Group × Sequence) is the random term.


❝ Now am Confused:ponder:,Which is the correct one?


Mine. For the exact setup ask a qualified SAS-coder.

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