Bioequivalence and Bioavailability Forum 02:47 CET

Main page Policy/Terms of Use Abbreviations Latest Posts

 Log in |  Register |  Search

f2 computation (for pts > 85%) [Dissolution / BCS / IVIVC]

posted by jag009 - NJ, 2018-09-10 18:41  - Posting: # 19257
Views: 695

Hi all,

One question related to f2 computation... According to guidance you only include one pt after 85 % release. But for drugs that don't show plateau after 85% (ie; even at one pt after 85%, the curve is still climbing) you have to include addition points right?

Thanks
John


Edit: Category changed; see also this post #1[Helmut]

Complete thread:

Activity
 Mix view
Bioequivalence and Bioavailability Forum |  Admin contact
18,882 posts in 4,026 threads, 1,271 registered users;
online 28 (1 registered, 27 guests [including 24 identified bots]).

Some scientists claim that hydrogen, because it is so plentiful,
is the basic building block of the universe.
I dispute that. I say there is more stupidity than hydrogen,
and that is the basic building block of the universe.    Frank Zappa

The BIOEQUIVALENCE / BIOAVAILABILITY FORUM is hosted by
BEBAC Ing. Helmut Schütz
HTML5 RSS Feed