f2 computation (for pts > 85%) [Dissolution / BCS / IVIVC]

posted by jag009  – NJ, 2018-09-10 18:41  – Posting: # 19257
Views: 1,972

Hi all,

One question related to f2 computation... According to guidance you only include one pt after 85 % release. But for drugs that don't show plateau after 85% (ie; even at one pt after 85%, the curve is still climbing) you have to include addition points right?

Thanks
John


Edit: Category changed; see also this post #1[Helmut]

Complete thread:

Activity
 Mix view
Bioequivalence and Bioavailability Forum |  Admin contact
19,688 posts in 4,178 threads, 1,352 registered users;
online 8 (0 registered, 8 guests [including 7 identified bots]).
Forum time (Europe/Vienna): 18:30 CEST

An expert is one who knows more and more
about less and less.    Nicholas Murray Butler

The BIOEQUIVALENCE / BIOAVAILABILITY FORUM is hosted by
BEBAC Ing. Helmut Schütz
HTML5