Bioequivalence and Bioavailability Forum • f2 computation (for pts

f2 computation (for pts > 85%) [Dissolution / BCS / IVIVC]

posted by jag009 – NJ, 2018-09-10 20:41 (2047 d 15:35 ago) – Posting: # 19257
Views: 5,584

Hi all,

One question related to f2 computation... According to guidance you only include one pt after 85 % release. But for drugs that don't show plateau after 85% (ie; even at one pt after 85%, the curve is still climbing) you have to include addition points right?

Thanks
John

Edit: Category changed; see also this post #1. [Helmut]

Complete thread:

f2 computation (for pts > 85%)jag009 2018-09-10 18:41 [Dissolution / BCS / IVIVC]
- f2 computation (for pts > 85%) ElMaestro 2018-09-10 22:52
  - f2 computation (for pts > 85%) jag009 2018-09-12 00:00
- f2 computation (for pts > 85%) Obinoscopy 2018-09-11 20:21
  - f2 computation (for pts > 85%) jag009 2018-09-12 00:01
    - f2 computation (for pts > 85%) - WHO GL Obinoscopy 2018-09-12 00:38
      - f2 computation (for pts > 85%) - WHO GL Helmut 2018-09-12 01:01
      - f2 computation (for pts > 85%) - WHO GL jag009 2018-09-12 20:35
        
        f2 computation (for pts > 85%) - WHO GL ElMaestro 2018-09-12 22:02