recoveries more than 100% [Bioanalytics]
The % recovery was 107.80%, 112.65% and 105.92% for the low quality control (LQC) and middle quality controls (MQC2 and MQC1), respectively. Whereas % recovery for higher quality control (HQC) was 98.25%.
The % recovery was determined by comparing the mean peak area of 6 replicates of extracted quality control samples at High, Middle and Low concentrations against respective mean peak area of 6 replicates of un-extracted quality control samples at High, Middle and Low concentrations. Internal standard used was deuterated.
Kindly confirm recoveries markedly higher than 100% for LQC, MQC2 and MQC1 are acceptable as per USFDA guidelines?? Also specify reason for higher recoveries.
- recoveries more than 100% - deepakpangavhane, 2018-09-03 08:28 [Bioanalytics]
- recoveries more than 100% - Ohlbe, 2018-09-03 19:21
- recoveries more than 100% - Ladi, 2018-09-04 03:51