visualization of power-law model [General Statistics]
❝ In case that the power law model used to assess dose proportionality consists only of fixed factors intercept and slope I would think a figure like Figure 1 and 3 in the Smith et al paper (Smith et al. , 2000. Confidence interval criteria for assessment of dose proportionality. Pharm Res. 17:1278-1283) is good way to go.
I think so.
❝ However, frequently the corresponding model includes period and sequence effect as additional fixed effects (e.g. Williams design) and I am looking for some thoughts how to adequately visualize the corresponding results (other than showing the observed data and corresponding predictions grouped by sequence and period in a lattice plot or residual plots).
For sake of simplicity I would go with the same plots as in the first case.
Only if period effects and/or sequence effects have a greater magnitude than the power law you will have a scatter in the data which seems not fit. I would expect such an behavior in only very rare cases, if any. If you have such a case, 'correct' your data for the period and/or sequence effects and plot then.
Hope you are well.
Regards,
Detlew
Complete thread:
- visualization of power-law model martin 2018-07-23 20:17 [General Statistics]
- visualization of power-law modeld_labes 2018-07-26 14:49