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visualization of power-law model [General Sta­tis­tics]

posted by martin - Austria, 2018-07-23 20:17  - Posting: # 19086
Views: 721

Dear colleagues,

I would be happy to get the forum members thoughts regarding graphical display of the outcome of a dose-proportionality assessment based on the power-law model

In case that the power law model used to assess dose proportionality consists only of fixed factors intercept and slope I would think a figure like Figure 1 and 3 in the Smith et al paper (Smith et al. , 2000. Confidence interval criteria for assessment of dose proportionality. Pharm Res. 17:1278-1283) is good way to go.

However, frequently the corresponding model includes period and sequence effect as additional fixed effects (e.g. Williams design) and I am looking for some thoughts how to adequately visualize the corresponding results (other than showing the observed data and corresponding predictions grouped by sequence and period in a lattice plot or residual plots).

Best regards

Martin

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