Manipulations with PK data in BE analysis [General Sta­tis­tics]

posted by ElMaestro  – Belgium?, 2018-07-18 23:19 (794 d 22:42 ago) – Posting: # 19080
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Hi Elena777,

I did not sanity-check the figures but at a glance it looks all normal and consistant with a standard BE study outcome.

Re. "manipulations": Data is typically log-transformed and then fit with a normal linear model with the four standard factors. If you use WNL with default settings it will fit Subject as random. From the model fit comes a set of effects for the factors, which give rise to treatment LSMeans (on the log scale). These are then backtransformed to the normal scale.

I could be wrong, but...

Best regards,
ElMaestro

R's base package has 274 reserved words and operators, along with 1761 functions. I can use 18 of them (about 14 of them properly). I believe this makes me the Donald Trump of programming.

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