Bioequivalence and Bioavailability Forum

Hi libaiyi,

❝ Is there any R package available for statistical analysis of william design or 3*3 design when there exists R, T1, T2?

The function sampleN.TOST() of package PowerTOST. After installing/attaching in the R-console or the command window of R Studio type known.designs() to see what is covered. In sampleN.TOST() use the argument design (i.e., design="3x6x3" for the six-sequence Williams’ design or design="3x3" for the Latin Square).
For low to moderate CVs sample sizes will be identical.