Pilot or pivotal ? [General Sta­tis­tics]

posted by Ohlbe – France, 2018-06-27 15:43 (1084 d 18:21 ago) – Posting: # 18981
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Hi ElMaestro,

» This is purely hypothetical for me. As far as I recall, I have not ever faced such a situation where two test formulations targeting the same authority were heads-on compared in a pivotal trial. I have faced it numerous times in pilot trials, but here the choice of formulation rarely is based on the CI but just on the observed GMR.

Precisely. But then, isn't this whole discussion on alpha correction purely hypothetical too ?

Sorry if I'm spoiling a nice thread...

Regards
Ohlbe

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