Any of two tests and one reference [General Sta­tis­tics]

posted by Helmut Homepage – Vienna, Austria, 2018-06-26 22:33 (974 d 06:20 ago) – Posting: # 18970
Views: 9,256

Hi ElMaestro,

» » […] if the goal is to prove the equivalence of any two of them (T1 and R or T2 and R).
» Due to the little word highlighted in red above I am fairly sure I would not apply any other alpha than 5%, meaning I would go with the usual 90% CIs. :-)

Good point – I missed that! In the past I did not adjust because only one will be marketed (i.e., the entire patient’s risk lies with this product). However, some regulatory statisticians (you know, coffee break chats) seem to be more strict because one gets two chances of passing. Too lazy to crawl the supplementary material of your paper about pilot studies: Is such a case covered?

Dif-tor heh smusma 🖖
Helmut Schütz

The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes

Complete thread:

 Admin contact
21,355 posts in 4,458 threads, 1,493 registered users;
online 4 (0 registered, 4 guests [including 2 identified bots]).
Forum time: Thursday 04:53 UTC (Europe/Vienna)

The rise of biometry in this 20th century,
like that of geometry in the 3rd century before Christ,
seems to mark out one of the great ages or critical periods
in the advance of the human understanding.    R.A. Fisher

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz