Any of two tests and one reference [General Sta­tis­tics]

posted by Helmut Homepage – Vienna, Austria, 2018-06-27 02:33 (2178 d 06:23 ago) – Posting: # 18970
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Hi ElMaestro,

❝ ❝ […] if the goal is to prove the equivalence of any two of them (T1 and R or T2 and R).


❝ Due to the little word highlighted in red above I am fairly sure I would not apply any other alpha than 5%, meaning I would go with the usual 90% CIs. :-)


Good point – I missed that! In the past I did not adjust because only one will be marketed (i.e., the entire patient’s risk lies with this product). However, some regulatory statisticians (you know, coffee break chats) seem to be more strict because one gets two chances of passing. Too lazy to crawl the supplementary material of your paper about pilot studies: Is such a case covered?

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