Any of two tests and one reference [General Sta­tis­tics]

posted by Helmut Homepage – Vienna, Austria, 2018-06-27 02:33 (2916 d 07:02 ago) – Posting: # 18970
Views: 20,216

Hi ElMaestro,

❝ ❝ […] if the goal is to prove the equivalence of any two of them (T1 and R or T2 and R).

❝

❝ Due to the little word highlighted in red above I am fairly sure I would not apply any other alpha than 5%, meaning I would go with the usual 90% CIs. :-)


Good point – I missed that! In the past I did not adjust because only one will be marketed (i.e., the entire patient’s risk lies with this product). However, some regulatory statisticians (you know, coffee break chats) seem to be more strict because one gets two chances of passing. Too lazy to crawl the supplementary material of your paper about pilot studies: Is such a case covered?
—
Dif-tor heh smusma 🖖🏼 Довге життя Україна! [image]
Helmut Schütz
[image]

The quality of responses received is directly proportional to the quality of the question asked. 🚮
Science Quotes

Complete thread:

UA Flag
Activity
 Admin contact
23,655 posts in 4,993 threads, 1,570 registered users;
152 visitors (0 registered, 152 guests [including 15 identified bots]).
Forum time: 09:35 CEST (Europe/Vienna)

Science is simply common sense at its best that is,
rigidly accurate in observation, and
merciless to fallacy in logic.    Thomas Henry Huxley

The Bioequivalence and Bioavailability Forum is hosted by
BEBAC Ing. Helmut Schütz
HTML5