## Impact of pooled variance (bias, CI) [Design Issues]

Hi Irene,

» Thank you for your explanation.

You are welcome. A picture tells more than a thousand words (AUC only).

The PE and its CI of T/R are similar. The small bias is caused by the fact that the average PE of S/R and T/S ($$\sqrt{141.09\times83.12}$$) is close to the T/R with 116.05. The other comparisons show negative biases. The CI of S/R is narrower in the pooled model and the CI of T/S is wider.
We don’t want to go there.

Dif-tor heh smusma 🖖
Helmut Schütz

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