Virtual Bioequivalence: a myth or coming reality? [Dissolution / BCS / IVIVC]
Dear All!
I was looking into the abstracts published after annual PAGE meeting (and had a pleasure to discuss it with some authors).
I collected some of them here for your review:
AFAIK regulatories are also interested and funding some of them.
What do you think? Is time of deconvolution over? Could we see new class A IVIVC using that approach soon?
I was looking into the abstracts published after annual PAGE meeting (and had a pleasure to discuss it with some authors).
I collected some of them here for your review:
- In vitro-in vivo correlation (IVIVC) population modeling for the in silico bioequivalence of a long-acting release formulation of Progesterone
- Automatic framework for bioequivalence studies from In Vitro test to In Vivo study design
- Defining level A IVIVC dissolution specifications based on individual in vitro dissolution profiles
- Selecting in vitro dissolution tests using population pharmacokinetic modelling to help bioequivalence studies
- Bayesian knowledge integration for an in vitro–in vivo correlation (IVIVC) model
AFAIK regulatories are also interested and funding some of them.
What do you think? Is time of deconvolution over? Could we see new class A IVIVC using that approach soon?
—
Kind regards,
Mittyri
Kind regards,
Mittyri
Complete thread:
- Virtual Bioequivalence: a myth or coming reality?mittyri 2018-06-09 22:39
- Virtual Bioequivalence: a myth or coming reality? jag009 2018-06-13 02:40
- Virtual Bioequivalence: a myth or coming reality? elba.romero 2018-10-19 01:17
- Virtual Bioequivalence: an update from PAGE (+TSD!) mittyri 2019-06-21 13:50
- FDA not concerned about the type I error? Helmut 2019-06-22 18:11
- Virtual Bioequivalence: a myth or coming reality? Helmut 2021-12-23 22:31
- Synovia is a nasty beast mittyri 2021-12-24 13:23
- Synovia is a nasty beast dshah 2022-01-10 15:31
- Synovia is a nasty beast mittyri 2021-12-24 13:23
- Virtual Bioequivalence: a myth or coming reality? Helmut 2022-02-17 12:06