Power decrease for the highly correlation of AUCt and AUCinf [Power / Sample Size]

posted by libaiyi – China, 2018-05-23 06:40 (973 d 18:49 ago) – Posting: # 18801
Views: 3,740

Hi, all

I want to ask about power calculation. In BE, Cmax, AUCt, and AUCinf are all needed for power consideration. And the power for each one need to be bigger than overall power for the accumulation of power. But AUCinf and AUCt are highly correlated, so could I decrease the individual power and only consider about AUCt and Cmax for the power setting?

Thanks in advance.

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